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Drug development

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New Scientist

MIT researchers have developed a new way of creating drug-carrying particles that could allow multiple doses of a vaccine to be delivered over an extended period of time, reports Matt Reynolds for New Scientist. “The technology could eventually be used to create ‘omni-vaccines’ that protect against a whole host of diseases in one shot.”

Boston Magazine

Boston Magazine reporter Rowan Walrath writes that MIT researchers have developed a new technique that could be used to deliver multi-drug vaccines. The researchers developed a new method for “designing customizable, three-dimensional microparticles that resemble minuscule coffee cups. Each cup…contains a drug or vaccine ‘library’ that can be released at multiple points over an extended period of time.”

Boston Globe

During a panel discussion during the Koch Institute’s 16th Annual Cancer Research Symposium, participants discussed how the convergence of biology and engineering could accelerate treatments for cancer and other diseases, writes Robert Weisman for the Boston Globe. “To my mind, this is the 21st century’s innovation story,” said President Emerita Susan Hockfield.

New Scientist

New Scientist reporter Andy Coghlan writes that MIT researchers have engineered bacteria to produce full-color, living photocopies. Coghlan explains that the technique could “enable finer control of the bacteria grown in fermenters to churn out vital drugs, antibodies and materials. Another application could be using light to sculpt living biomaterials, such as tissues and organs for transplant.”

The Wall Street Journal

Wall Street Journal reporter James Hagerty writes about the life and legacy of Henri Termeer, a life member of the MIT Corporation known for his work as a pioneering leader in the field of biotechnology.

Xconomy

Xconomy reporter Ben Fidler writes about the life and legacy of Henri Termeer, a life member of the MIT Corporation who died at age 71. Institute Prof. Phillip Sharp explains that Termeer was, “a transformational leader in biotechnology of orphan diseases. Many children now have hope of a healthy life because of his vision and 40 years of creative business leadership.”

Boston Globe

Henri Termeer, a life member of the MIT Corporation who was known as one of the founding fathers of the biotech industry, died at age 71, write Robert Weisman and Bryan Marquard for The Boston Globe. Termeer was, “a key leader in the biotech revolution that placed Massachusetts at the nexus of cutting-edge research and development.”

The Atlantic

MIT researchers have developed a new technique for making vaccines using freeze-dried cells, reports Ed Yong for The Atlantic. Yong explains that in addition to producing medicines, the technique provides a new way of “detecting important diseases, like Zika and Ebola, without relying on laboratories or sequencing machines.”

STAT

Eric Boodman writes for STAT that MIT researchers have developed a technique to produce biopharmaceuticals in remote locations. “Instead of making the drugs and then trying to keep them refrigerated over thousands of miles,” Boodman writes, the researchers, “want to give people the ingredients. These components don’t require refrigeration, and the instructions are as simple as they come: Just add water.”

Popular Science

Popular Science reporter Sarah Chodosh writes that MIT researchers have developed a strategy to deliver beneficial bacteria to the GI tract. The researchers used layers of different sugars "to coat individual cells of Bacillus coagulans, which is used to treat irritable bowel syndrome." 

Wired

Prof. Linda Griffith speaks with Wired reporter Sarah Zhang about her work developing chips that can mimic human organs in an effort to better understand interactions between the immune system and the liver. Griffith is currently working to connect at least 10 miniature organs on a chip to study, for example, how breast cancer can spread to the liver.

National Public Radio (NPR)

NPR's Martha Bebinger speaks with Prof. Allan Myerson about the system he and his colleagues developed to manufacture drugs on demand. “These are portable units so you can put them on the back of a truck and take them anywhere,” he explains. “If there was an emergency, you could have these little plants located all over.”

Popular Science

In a roundup of top science images of the week, Popular Science reporter Claire Maldarelli highlights a new machine developed by MIT researchers “that can synthesize multiple kinds of drugs, including antidepressants, antihistamines, and a local anesthetic.”

Scientific American

Scientific American reporter Bob Roehr writes that MIT researchers have developed a manufacturing system that can produce a variety of drugs. The researchers created a “drug-producing process that is not only faster but also more precise, more efficient and cheaper than production methods now in use," explains Roher. 

Science

Science reporter Robert Service writes that MIT researchers have developed a drug synthesis machine that can produce a variety of medications. Service writes that such a machine “could someday help pharmaceutical companies meet unexpected surges in demand and help health officials respond to disasters and medical emergencies worldwide by producing medicines when and where they are needed.”