A new framework to efficiently screen drugs
Novel method to scale phenotypic drug screening drastically reduces the number of input samples, costs, and labor required to execute a screen.
MIT chemists synthesize plant-derived molecules that hold potential as pharmaceuticals
Large multi-ring-containing molecules known as oligocyclotryptamines have never been produced in the lab until now.
MIT engineers find a way to protect microbes from extreme conditions
By helping microbes withstand industrial processing, the method could make it easier to harness the benefits of microorganisms used as medicines and in agriculture.
Creating the crossroads
Through academia and industry, Gevorg Grigoryan PhD ’07 says there is no right path — just the path that works for you.
CHARMed collaboration creates a potent therapy candidate for fatal prion diseases
A new gene-silencing tool shows promise as a future therapy against prion diseases and paves the way for new approaches to treating disease.
MIT-Takeda Program wraps up with 16 publications, a patent, and nearly two dozen projects completed
The program focused on AI in health care, drawing on Takeda’s R&D experience in drug development and MIT’s deep expertise in AI.
A smarter way to streamline drug discovery
The SPARROW algorithm automatically identifies the best molecules to test as potential new medicines, given the vast number of factors affecting each choice.
Scientists identify mechanism behind drug resistance in malaria parasite
SMART researchers find a cellular process called transfer ribonucleic acid (tRNA) modification influences the malaria parasite’s ability to develop resistance.
Taking RNAi from interesting science to impactful new treatments
Alnylam Pharmaceuticals, founded by MIT professors and former postdocs, has turned the promise of RNAi research into a new class of powerful therapies.
Improving drug development with a vast map of the immune system
Immunai’s founders were researchers at MIT when they launched their company to help predict how patients will respond to new treatments.
Unlocking mRNA’s cancer-fighting potential
MIT spinout Strand Therapeutics has developed a new class of mRNA molecules that can sense where they are in the body, for more targeted and powerful treatments.
DNA particles that mimic viruses hold promise as vaccines
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
A new way to deliver drugs more efficiently
Core-shell structures made of hydrogel could enable more efficient uptake in the body.
2023-24 Takeda Fellows: Advancing research at the intersection of AI and health
Thirteen new graduate student fellows will pursue exciting new paths of knowledge and discovery.
Studying cancer in context to stop its growth
MIT spinout Kronos Bio, founded by Associate Professor Angela Koehler, studies the complex signaling networks of cancer cells to find new drug targets.