Popular Science reporter Hannah Seo writes that MIT researchers have developed a way to watch and record how the microscopic scales on a butterfly’s wings grow and tile themselves as the butterfly develops inside its chrysalis. The researchers hope to “use butterfly scales as inspiration for the design of new materials,” writes Seo. “Butterfly scales have other fascinating properties such as water repellency and the ability to regulate temperature.”
Researchers from MIT have developed a 3-D printable ink made from bacterial cells that can release anti-cancer drugs or remove toxins from the environment, reports Carissa Wong for New Scientist. This is the first of its kind,” says research affiliate Avinash Manjula-Basavanna. “A living ink that can respond to the environment. We have repurposed the matrix that these bacteria normally utilise as a shielding material to form a bio-ink.”
ARS Technica senior writer Jennifer Ouellette spotlights MIT researchers who have successfully recorded the structural growth of butterfly wings inside its chrysalis for the first time. “A lot of these stages were understood and seen before, but now we can stitch them all together and watch continuously what’s happening, which gives us more information on the detail of how scales form,” says research assistant Anthony McDougal.
Nature reporter Eric Bender spotlights MIT startup Kytopen, which has developed a microfluidic platform to create induced pluripotent stem (iPS) cells and other forms of cell therapy. We want to do minimally invasive surgery,” says Kytopen co-founder Prof. Cullen Buie.
Singapore-MIT Alliance for Research and Technology (SMART) researchers have developed a new lab-free immune profiling assay that can be used “to better profile aggressive, rapidly changing host immune response in cases of infection, for example COVID-19,” reports HealthCare Asia Daily.
New Scientist reporter Layal Liverpool writes that a new study co-authored by MIT researchers finds that “synthetic cells made by combining components of Mycoplasma bacteria with a chemically synthesised genome can grow and divide into cells of uniform shape and size, just like most natural bacterial cells.”
A new assay developed by researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), can profile the “rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves,” reports the Scientific Inquirer.
Research affiliate Fei Chen and his colleagues have developed a new method that could be used to uncover the organization and sequence of DNA inside intact cells, reports Nature. The new method could be used to “help to reveal how genome organization changes with disease.”
European Pharmaceutical Review reporter Hannah Balfour writes that researchers from the Singapore-MIT Alliance for Research and Technology have developed a new dissolvable gelatin microcarrier that can help enhance cell production. “Innovations in microcarriers will aid in the scalability of certain cell types such as mesenchymal stromal cells for cell-based therapy, including for regenerative medicine applications,” says Associate Provost Krystyn Van Vliet.
Researchers from the Singapore-MIT Alliance for Research and Technology (SMART) Critical Analytics for Manufacturing Personalized Medicine (CAMP) research group have been awarded new research grants aimed at supporting work exploring personalized medicine and cell therapy, reports Health Europa. “In addition to our existing research on our three flagship projects, we hope to develop breakthroughs in manufacturing other cell therapy platforms that will enable better medical treatments and outcomes for society,” says Associate Provost Krystyn Van Vliet.
Prof. Aviv Regev speaks with the Associated Press about the Human Cell Atlas Consortium, which is aimed at cataloging all the cells in the human body in an effort to better understand human diseases. "This is not going to cure all disease immediately," she says, but "it is a critical stepping stone."
Prof. Aviv Regev speaks with NPR’s Nell Greenfieldboyce about her work with the Human Cell Atlas trying to catalogue every cell in the human body. “We don't need to analyze every individual cell out of 37 trillion because the cells kind of repeat themselves,” says Regev. “All we need to do is sample enough of them from enough region in order to get comprehensive coverage.”
STAT reporter Kate Sheridan writes about MIT startup SQZ Biotech, which is developing a “technology that will squeeze cells to open up tiny pores in their membranes to deliver gene therapies or medicines straight into the cell.”
Wired reporter Megan Molteni highlights Prof. Aviv Regev’s work leading the Human Cell Atlas, an effort to catalog the cells in the human body that could eventually serve as a roadmap for understanding and treating disease. “From the beginning we have designed this as a public good and an open resource to enable science around the world,” Regev explains.
Prof. Aviv Regev speaks with WBUR’s Karen Weintraub about her work exploring human cells. Regev says she was inspired to study the human cell as, “it’s this phenomenal entity that knows how to take many different pieces of information, make very quick and sophisticated decisions, act on them and continue on its way.”