The way sensory prediction changes under anesthesia tells us how conscious cognition works
A new study adds evidence that consciousness requires communication between sensory and cognitive regions of the brain’s cortex.
Research quantifying “nociception” could help improve management of surgical pain
New statistical models based on physiological data from more than 100 surgeries provide objective, accurate measures of the body’s subconscious perception of pain.
Study assesses seizure risk from stimulating the thalamus
In animal models, even low stimulation currents can sometimes still cause electrographic seizures, researchers found.
New method enables fast, accurate estimates of cardiovascular state to inform blood pressure management
A mathematical method, validated with experimental data, provides a fast, reliable, and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care.
Study reveals how an anesthesia drug induces unconsciousness
Propofol, a drug commonly used for general anesthesia, derails the brain’s normal balance between stability and excitability.
Study models how ketamine’s molecular action leads to its effects on the brain
New research addresses a gap in understanding how ketamine’s impact on individual neurons leads to pervasive and profound changes in brain network function.
Anesthesia technology precisely controls unconsciousness in animal tests
An advanced closed-loop anesthesia delivery system that monitors brain state to tailor propofol dose and achieve exactly the desired level of unconsciousness could reduce post-op side effects.
Summer research offers a springboard to advanced studies
Three graduate students forged a path to the same Picower Institute lab through participating in the MIT Summer Research Program in Biology and Neuroscience.
Study finds tracking brain waves could reduce post-op complications
Distinctive EEG patterns indicate when a patient’s state of unconsciousness under general anesthesia is more profound than necessary.
Studying consciousness without affecting it
A new study tests an alternative to external stimulation for measuring when subjects lose and regain responsiveness during sedation and anesthesia.
Are Covid-19 “comas” signs of a protective hibernation state?
Scientists hypothesize that, as in a hibernating turtle, the brain under sedation and deprived of oxygen may assume a protective state.
Celebrating 20 years of discovery, Picower Institute looks ahead to continuing impact
At an exhibition marking two decades since a transformative gift from the Picower Foundation, current and alumni members described research at the forefront of neuroscience and beyond.
Emery Brown wins a share of 2022 Gruber Neuroscience Prize
Brown and three other scientists recognized for advancing statistical, theoretical analyses of neuroscience data.
Emery Brown earns American Institute for Medical and Biological Engineering Pierre Galletti Award
AIMBE's highest honor recognizes MIT professor's contributions to neural signal processing, anesthesiology advances.
3 Questions: Emery Brown on improving anesthesia with neuroscience
Professor describes a new research center he is working to develop where researchers will seek to improve patient care by integrating neuroscience and anesthesiology.